The letters have arrived at a rate of knots since the PM was forced to apologise over his handling of the Chris Pincher scandal, as it emerged he'd forgotten about being told of previous allegations of "inappropriate" conduct.

Politics Hub: More resignations as pressure mounts on PM - live updates

So who has said they will stay or go?

Rishi Sunak is undoubtedly the most significant resignation. The chancellor said that he could no longer remain loyal to the prime minister.

Health Secretary Sajid Javid also resigned. He said the British people "expect integrity from their government", but voters now believed the current administration was neither competent nor "acting in the national interest".

Wales Secretary Simon Hart resigned on Wednesday night, saying everything had been done to "turn the ship around" but "it is with sadness that I feel we have passed the point where this is possible".

Brandon Lewis has resigned as Northern Ireland Secretary, telling the PM that government requires "honesty, integrity and mutual respect".

Michelle Donelan has resigned as Education Secretary - less than 36 hours in the job, telling the PM: "I see no way that you can continue in post."

Children and families minister Will Quince has resigned, saying he had "no choice" after appearing on Sky News on Monday to defend Mr Johnson using Number 10 briefings "which have now been found to be inaccurate".

Schools minister Robin Walker was next to go. He said the Government has been "overshadowed by mistakes and questions about integrity".

Victoria Atkins has resigned as a justice minister, saying "I can no longer pirouette around our fractured values" and "we can and must be better than this".

Treasury minister John Glen has resigned, telling Boris Johnson "I can no longer reconcile my commitment to the role" with "the complete lack of confidence I have in your continuing leadership of our country".

Environment minister Jo Churchill also criticised the PM in her resignation, calling for a leader with integrity and competence rather than a "jocular self-serving approach."

Stuart Andrew has resigned as housing minister, saying "our party, particularly our members and more importantly our great country, deserve better".

Mims Davies has resigned as employment minister, saying the Conservative Party needed a "fresh start".

Five junior ministers coordinated their resignations, signing a letter together. They are Kemi Badenoch, Neil O'Brien, Alex Burghart, Lee Rowley and Julia Lopez.

Rachel Maclean resigned as minister for safeguarding at the Home Office, saying the prime minister should "resign for the good of the country and our party".

Mike Freer has resigned as minister for exports and minister for equalities, complaining about "creating an atmosphere of hostility for LGBT+ people", adding "I can no longer defend policies I fundamentally disagree with".

Edward Argar has resigned as health minister, saying: "I fear that a change is needed in order for our party to continue to deliver on our shared ambitions for our country."

Helen Whately has resigned as Treasury minister, telling Mr Johnson: "I have argued that you should continue as prime minister many times in recent months, but there are only so many times you can apologise and move on. That point has been reached."

Damian Hinds has resigned as security minister, saying: "It shouldn't take the resignation of dozens of colleagues, but for our country, and trust in our democracy, we must have a change of leadership."

George Freeman has resigned as science minister, telling the PM: "The chaos in your cabinet and No 10 this month is destroying our credibility. It can't go on."

Guy Opperman has resigned as pensions minister, telling Mr Johnson: "Sadly, recent events have shown clearly that government simply cannot function with you in charge."

Chris Philp has resigned as technology minister, telling the PM "integrity, honesty and trust" are important in public life and that he should "step down".

James Cartlidge has resigned as courts' minister, saying it is "no longer even remotely possible" for the PM to "change and reset".

Caroline Johnson has resigned as vice chair of the Conservative Party, saying: "The cumulative effect of your errors of judgement and domestic actions have squandered the goodwill of our great party."

Luke Hall has resigned as deputy chair of the Conservative Party, saying: "The current situation is clearly untenable."

Rebecca Pow has resigned as environment minister, saying: "Values, integrity and the morals by which I live are at stake, and the needs of the country must always come first."

Who else has said they are going:

• Laura Trott has resigned as parliamentary private secretary at the Department of Transport
• Alex Chalk resigned as solicitor general
• Andrew Murrison resigned as trade envoy to Morocco
• Bim Afolami has resigned as Tory vice chair

• Jonathan Gullis has resigned as parliamentary private secretary to the Northern Ireland secretary
• Saqib Bhatti has resigned as parliamentary private secretary to the health secretary
• Nicola Richards has resigned as parliamentary private secretary for the Department for Transport
• Virginia Crosbie has quit her role as parliamentary private secretary at the Welsh Office

• Claire Coutinho has resigned as a parliamentary private secretary to the Treasury
• David Johnston has resigned as a parliamentary private secretary for the Department for Education
• Felicity Buchan has resigned as parliamentary private secretary in the Department of Business, Energy and Industrial Strategy
• Selaine Saxby has resigned as parliamentary private secretary at the Treasury

• Duncan Baker has resigned as parliamentary private secretary in the Department for Levelling Up, Housing and Communities
• Craig Williams has resigned as parliamentary private secretary to the chancellor
• Mark Logan resigned as parliamentary private secretary to the Ministers for Northern Ireland
• Theo Clarke has resigned as the prime minister's trade envoy to Kenya

• Mark Fletcher has resigned as parliamentary private secretary in the Department for Business
• Sara Britcliffe has resigned as parliamentary private secretary in the Department for Education
• Ruth Edwards has resigned as parliamentary private secretary in the Scotland Office
• Peter Gibson has resigned as parliamentary private secretary in the Department for Trade

• David Duguid has resigned as a trade envoy for Angola and Zambia
• James Sunderland has resigned as parliamentary private secretary in the Department for Environment, Food and Rural Affairs
• Jacob Young has resigned as parliamentary private secretary in the Department for Levelling Up
• James Daly has resigned as parliamentary private secretary at the Department for Work and Pensions

• David Mundell has resigned as trade envoy for New Zealand
• Danny Kruger has resigned as parliamentary private secretary at the Department for Levelling Up
• Gareth Davies has resigned as parliamentary private secretary at the Department of Health
• James Davies has resigned as parliamentary private secretary at the Department of Health

• Rob Butler has resigned as parliamentary private secretary at the Foreign Office
• Richard Graham has resigned as a trade envoy to several south-east Asian nations, saying it is vital to "have full confidence in the leadership and integrity of the government that I represent".

Who has been sacked?

• Levelling Up, Housing and Communities Secretary Michael Gove was sacked by the prime minister

Who has been promoted?

• Nadhim Zahawi has been moved from education secretary to chancellor.

• Steve Barclay, chancellor of the Duchy of Lancaster and minister for the Cabinet Office, has been promoted to health secretary.

• Greg Clark, the former business secretary under Theresa May, will replace Michael Gove as levelling up secretary.

• Kit Malthouse has been promoted from policing minister to become the new Chancellor for the Duchy of Lancaster - the most senior minister in the Cabinet Office after the prime minister.

• James Cleverly has been moved from the Foreign Office, where he was minister for Europe and North America, to become the next education secretary.

• Robert Buckland, the former justice secretary, is the new Welsh secretary.

• Shailesh Vara is the new Northern Ireland secretary.

• Andrew Stephenson has been appointed Minister without Portfolio, and will attend cabinet.

Who has said they are staying:

• Justice Secretary Dominic Raab - a spokesperson said Mr Raab is "loyal to the prime minister".
• Culture Secretary Nadine Dorries - she said the PM's priority is to "continue to deliver on the promises he made and the British public voted for".
• Brexit opportunities minister Jacob Rees-Mogg - he told Sky News "the prime minister won a large mandate in a general election, a vote of the British people and that should not be taken away from him because a number of people resign".
• Scotland Secretary Alister Jack - he said "I fully support the prime minister".
• Attorney General Suella Braverman has said she will continue in her post, despite calling on the PM to resign and saying she will put her name into the ring if there is a leadership contest.
• Business Secretary Kwasi Kwarteng
• Home Secretary Priti Patel
• Defence Secretary Ben Wallace - has said he is staying in post along with a number of others who "have an obligation to keep this country safe, no matter who is PM".
• International Trade Secretary Anne-Marie Trevelyan
• Foreign Secretary Liz Truss
• Transport Secretary Grant Shapps
• Chief whip Chris Heaton-Harris
• Cabinet minister Alok Sharma
• Cabinet minister Michael Ellis
• Chief Secretary to the Treasury Simon Clarke
• Lord Privy Seal, and Leader of the House of Lords Baroness Evans
• Secretary of State at the Department for Work and Pensions Therese Coffey - has said she will remain in office to ensure the "wheel of government keep turning".