Ten fire engines and about 70 firefighters were called to a blaze at a property on Channel Close in Hounslow, just before 10.30pm on Sunday night.

The ground floor and first floors of the mid-terraced house were destroyed and part of the roof was also damaged.

The fire was under control by 1.30am on Monday.

Five people on the first floor of the building were pronounced dead at the scene.

A man was taken to hospital and one person remains unaccounted for.

London Fire Commissioner Andy Roe said: "This is a terribly sad incident and the thoughts of all of us at London Fire Brigade are with the family, friends and all those affected at this difficult time.

"Staff will be in the local community today to offer support and advice where needed.

"The welfare of our staff is very important and all those involved will be offered support from our counselling and trauma service."

The cause of the fire is being investigated.